2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W1006754
    NNMT-IN-7 1973504-60-7 98.0%
    NNMT-IN-7 is a nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 505.7 μM against human targets. NNMT-IN-7 inhibits the catalytic activity of NNMT, an enzyme responsible for mediating N-methylation modification of endogenous and exogenous xenobiotics. NNMT-IN-7 can be used in research related to obesity and type 2 diabetes.
    NNMT-IN-7
  • HY-W1008068
    3'-O-TBDMS-2'-dG(iBu) 99540-94-0 98%
    3'-O-TBDMS-2'-dG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
    3'-O-TBDMS-2'-dG(iBu)
  • HY-W1008071
    3'-O-TBDMS-2'-O-Me-rG(iBu) 863097-97-6
    3'-O-TBDMS-2'-O-Me-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
    3'-O-TBDMS-2'-O-Me-rG(iBu)
  • HY-W1008628
    5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu) 206055-72-3
    5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
    5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu)
  • HY-W103960R
    Mirabegron impurity-1 (Standard) 391901-45-4
    Mirabegron impurity-1 (Standard) is the analytical standard of Mirabegron impurity-1. This product is intended for research and analytical applications. Mirabegron impurity-1 is a potent and selective β3- adrenergic receptor agonist. Mirabegron impurity-1 has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used in the study of the study of bladder impurity .
    Mirabegron impurity-1 (Standard)
  • HY-W104368R
    Nicotinic acid riboside (Standard) 17720-18-2 98%
    Nicotinic acid riboside (Standard) is the analytical standard of Nicotinic acid riboside (HY-W104368). This product is intended for research and analytical applications. Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism.
    Nicotinic acid riboside (Standard)
  • HY-W1052697
    (R)-DPPE-mPEG2000 205494-72-0 98%
    (R)-DPPE-mPEG(2000) is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    (R)-DPPE-mPEG2000
  • HY-W1121519
    6,6′-Trehalose dioleate 338733-40-7 98%
    6,6′-Trehalose dioleate is a glycolipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    6,6′-Trehalose dioleate
  • HY-W1121728
    3'-O-TBDMS-2'-F-dA(Bz) 1244763-25-4
    3'-O-TBDMS-2'-F-dA(Bz) is a monomeric raw material that can be used for nucleic acid synthesis.
    3'-O-TBDMS-2'-F-dA(Bz)
  • HY-W1121735
    DMTr-2'-O-TBDMS-5-F-rU-3'-CE-phosphoramidite 173241-78-6 98%
    DMTr-2'-O-TBDMS-5-F-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
    DMTr-2'-O-TBDMS-5-F-rU-3'-CE-phosphoramidite
  • HY-W1121759
    DMTr-2'-ara-F-dG(dmf)-3'-CE-phosphoramidite 1391913-24-8 98%
    DMTr-2'-ara-F-dG(dmf)-3'-CE-Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
    DMTr-2'-ara-F-dG(dmf)-3'-CE-phosphoramidite
  • HY-W1121770
    DMTr-2'-O-Propargyl-rU-3'-CE-phosphoramidite 171486-62-7 98%
    DMTr-2'-O-propargyl-rU-3'-CE -Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
    DMTr-2'-O-Propargyl-rU-3'-CE-phosphoramidite
  • HY-W1121803
    2'-F T Amidite 182700-06-7 98%
    2'-F T Amidite (DMTr-2'-F-dT-3'-CE-phosphoramidite) is a monomeric raw material that can be used for nucleic acid synthesis.
    2'-F T Amidite
  • HY-W1124251
    3'-O-TBDMS-2'-F-dG(iBu) 2382967-92-0
    3'-O-TBDMS-2'-F-dG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
    3'-O-TBDMS-2'-F-dG(iBu)
  • HY-W1130405
    ((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate) 2036273-20-6 98%
    ((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate) is an ionizable cationic lipid (pKa = 4.67) and a derivative of ALC-0315).
    ((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate)
  • HY-W127504A
    Rac-Sodium ricinoleate 475680-30-9 98%
    Rac-Sodium ricinoleate is an ester product.
    Rac-Sodium ricinoleate
  • HY-W130074R
    α-Pinene oxide (Standard) 1686-14-2
    α-Pinene oxide (Standard) is the analytical standard of α-Pinene oxide (HY-W130074). This product is intended for research and analytical applications. α-Pinene oxide is a type of monoterpene epoxidation intermediate. α-Pinene oxide is produced via the cytochrome P-450-mediated oxidation pathway in Dendroctonus terebrans body microsomes and rat liver microsomes, and can be further converted into alcohols, ketones and insect pheromone derivatives. α-Pinene oxide can generate the perfume intermediate myrtenal. α-Pinene oxide is used in studies related to terpenoid metabolism and perfume synthesis.
    α-Pinene oxide (Standard)
  • HY-W131351R
    N-Heptadecane (Standard) 629-78-7
    N-Heptadecane (Standard) is the analytical standard of N-Heptadecane. This product is intended for research and analytical applications. N-Heptadecane (Heptadecane) is an ester product.
    N-Heptadecane (Standard)
  • HY-W131352R
    Hexacosane (Standard) 630-01-3
    Hexacosane (Standard) is the analytical standard of Hexacosane. This product is intended for research and analytical applications. Hexacosane (N-Hexacosane) is an ester product.
    Hexacosane (Standard)
  • HY-W131353R
    Hexatriacontane (Standard) 630-06-8
    Hexatriacontane (Standard) is the analytical standard of Hexatriacontane. This product is intended for research and analytical applications. Hexatriacontane (ALKANE C36) is an ester product.
    Hexatriacontane (Standard)
Cat. No. Product Name / Synonyms Application Reactivity